Is Unisom safe to use during pregnancy?

Unisom, a brand name for the antihistamine doxylamine, is generally considered safe to use during pregnancy for managing symptoms of morning sickness when used as directed. Obstetricians and gynecologists often recommend it in combination with vitamin B6 (pyridoxine) as a first-line treatment for nausea and vomiting in pregnancy. The American College of Obstetricians and Gynecologists (ACOG) supports the use of doxylamine and vitamin B6 as an effective and safe treatment, which has been validated by numerous studies. However, it is important that pregnant women consult their healthcare provider before starting any new medication, including Unisom, to ensure it is appropriate for their specific medical condition and to discuss potential risks and benefits.